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When switching from other contraceptive procedures, Depo-Provera CI must be given in a very manner that makes certain steady contraceptive protection primarily based on the mechanism of motion of both techniques, (e.

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Problems of problem for estrogen deficiency and reduced HDL concentrations theoretically raising cardiovascular threat:

You’re quickly secured just after acquiring the first Depo shot if you get it throughout your menstrual time period. If you will get the shot at Yet another time for the duration of your cycle, you may have to attend every week to 10 days prior to possessing intercourse with no condom to stop pregnancy.

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Any affected individual who develops thrombosis though undergoing therapy with Depo-Provera CI really should discontinue treatment Unless of course she has no other suitable options for start control.

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The Women's Overall health Initiative investigated the usage of a mix of oral CEEs and MPA in comparison to placebo. The research was prematurely terminated when Formerly unpredicted threats ended up uncovered, particularly the discovering that although the all-result in mortality was not affected via the hormone therapy, some great benefits of menopausal hormone therapy (diminished hazard of hip fracture, colorectal and endometrial most cancers and all other causes of Dying) were being offset by amplified danger of coronary heart disease, breast most cancers, strokes and pulmonary embolism.[ninety]

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